Latest Diabetes Drug Saxagliptin for Uncontrolled Diabetes
The latest or the newest diabetes medicine is here in the form of a new class of drugs that overcomes the limitations of earlier generations of medications for diabetes.
Two multinational companies have mutually launched in India a new drug called saxagliptin belonging to a group of molecules increasingly prescribed by doctors for patients with uncontrolled diabetes. These two companies, Bristol-Myers Squibb and Astra Zeneca, have stated that India is the first country in Asia where saxagliptin will be available. Saxagliptin. The latest diabetes medicine releases in India, 9 months after the debut in US. A diabetic has to take one dose daily; it costs Rs. 38 per tablet.
Presently, there are two other medications sitagliptin and vildagliptin that work the same way as saxagliptin. “These molecules are very effective – especially for patients whose diabetes has progressed to a point where conventional medicines are not useful,” said Anoop Misra, director of diabetes and metabolic diseases division of Fortis Hospital New Delhi. “However, a new drug to the same class of molecules directly benefit patients if competition drives down prices,” said Misra.
When patients are not able to control diabetes with diet and exercise, doctors prescribe a drug called metformin, or, eventually, a class of drugs known as second generation sulfonylureas. But even these drugs have certain limitations. The side effects include hypoglycemia, a potentially dangerous ‘blood sugar too low’ case and weight gain. But the gliptins do not have such problems.
Endocrinologists state that 60 percent of patients with diabetes are oral medications. Among these, approximately one third would be with metformin or sulfolnylurea, another third would require a combination of metformin and sulfonylurea, while the others have progressed to a point that would need gliptin gliptin or in combination with one of the other two drugs.
Studies imply that India has more than 40 million patients with diabetes. Drug industry officials estimate that the annual market for diabetes drugs in India is worth Rs 2,000 crores
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Posted by Starwin on 2nd April, 2010
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